Glioblastoma-Diagnosis and Treatment

Journal of Cancer Research and Immuno-Oncology is an open access rapid peer reviewed journal in the field of cancer research. Here we discuss about Glioblastoma- Diagnosis and Treatment.

Glioblastoma is an aggressive type of cancer that can occur in the brain or spinal cord. Glioblastoma forms from cells called astrocytes that support nerve cells.

Glioblastoma can occur at any age, but tends to occur more often in older adults. It can cause worsening headaches, nausea, vomiting and seizures.

Glioblastoma, also known as glioblastoma multiforme, can be very difficult to treat and a cure is often not possible. Treatments may slow progression of the cancer and reduce signs and symptoms.

Diagnosis

Tests and procedures used to diagnose glioblastoma include:

• Neurological exam. During a neurological exam, your doctor will ask you about your signs and symptoms. He or she may check your vision, hearing, balance, coordination, strength and reflexes. Problems in one or more of these areas may provide clues about the part of your brain that could be affected by a brain tumor.
• Imaging tests. Imaging tests can help your doctor determine the location and size of your brain tumor. MRI is often used to diagnose brain tumors, and it may be used along with specialized MRI imaging, such as functional MRI and magnetic resonance spectroscopy.

Other imaging tests may include CT and positron emission tomography (PET).

• Removing a sample of tissue for testing (biopsy). 

Treatment

Glioblastoma treatment options include:

• Surgery to remove the glioblastoma. 
•  Radiation therapy. 

 Radiation therapy is usually recommended after surgery and may be combined with chemotherapy. For people who can't undergo surgery, radiation therapy and chemotherapy may be used as a primary treatment.

• Chemotherapy: Chemotherapy uses drugs to kill cancer cells. In some cases, thin, circular wafers containing chemotherapy medicine may be placed in your brain during surgery. The wafers dissolve slowly, releasing the medicine and killing cancer cells.

After surgery, the chemotherapy drug temozolomide (Temodar) — taken as a pill — is often used during and after radiation therapy.

Other types of chemotherapy may be recommended if your glioblastoma recurs. These other types of chemotherapy are often administered through a vein in your arm.

• Tumor treating fields (TTF) therapy. 

 TTF is combined with chemotherapy and may be recommended after radiation therapy.

• Targeted drug therapy. 

 Bevacizumab (Avastin) targets the signals that glioblastoma cells send to the body that cause new blood vessels to form and deliver blood and nutrients to cancer cells. Bevacizumab may be an option if your glioblastoma recurs or doesn't respond to other treatments.

• Clinical trials.
• Supportive (palliative) care. 

Journal of cancer research and immune-oncology announces papers for the upcoming issue. Interested can submit their manuscript through online portal.

Submit manuscript at https://www.longdom.org/submissions/cancer-research-immuno-oncology.html or send as an e-mail attachment to the Editorial Office at cancerresearch@clinicalres.org

Media contact:

Maegan Smith

Managing Editor

Journal of Cancer Research and Immuno-Oncology

Mail ID: cancerresearch@clinicalres.org

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